Budderweeds Canada has experienced a shift in perception regarding cannabis, which historically faced stigma due to its effects. Now, it is increasingly recognized for its potential benefits in various medical fields. Recent years have witnessed heightened research into the therapeutic properties of cannabis, especially concerning its advantages for neurological conditions.
Aside from its well-known applications for stress relief, reducing depression, and enhancing sleep, cannabis shows potential in managing a wide range of neurological disorders. This article explores five specific conditions and how cannabis or cannabis plays a crucial role in their therapeutic applications.
Table of Contents
Key Takeaways:
- Certain cannabinoids and terpenes display unique effects on various neurological disorders.
- Linalool, myrcene, and limonene demonstrate anti-convulsant properties.
- Equal ratios of THC and CBD, along with other cannabis compounds, show promise in cancer treatment.
A Natural Approach to Managing Neurological Disorders
Addressing complex conditions such as Alzheimer’s disease (AD), brain tumors, Parkinson’s disease (PD), intractable epilepsy, and chronic traumatic encephalopathy (CTE) or traumatic brain injury (TBI) varies according to individual patient needs and the severity of their condition.
Cannabis is a Viable Treatment Option
Epilepsy
The endocannabinoid system plays a role in influencing seizure thresholds. THC, in particular, has been shown to effectively stop seizures, unlike traditional medications. Animal studies have demonstrated significant increases in endocannabinoid production and sustained increases in CB1 production over time. Researchers have noted the anti-convulsant characteristics of cannabinoids even at non-sedative levels.
Research has focused on THC, THCA, and linalool, a terpenoid present in cannabis. The conversation surrounding THCA is intricate, with ongoing discussions about its activity at the CB1 receptor versus its conversion to THC.
Recent discoveries have also highlighted the anti-convulsant effects of cannabidiolic acid (CBDA), suggesting its serotonergic influences. CBDA shows a considerably higher affinity for the 5-HT1A receptor compared to CBD.
If you’re interested in exploring cannabis vape pens for your condition, seek out products containing THC, CBD, THCA, or linalool.
OneStop – THC Distillate Disposable Vape pen Skittlez features linalool as a primary terpene, with THC concentrations ranging from 16 to 21%.
Brain Tumors
Numerous studies have investigated the use of cannabis in patients diagnosed with brain tumors. A 2006 study published in the British Journal of Cancer found that administering THC directly into tumors in patients with glioblastoma multiforme (GBM) extended their lifespans slightly beyond expectations in nine cases.
A case report in the Journal of Child’s Nervous System documented complete regression of residual tumors in two children with pilocytic astrocytomas after smoking cannabis.
THCA acts as a peroxisome proliferator-activated receptor-gamma (PPARγ) agonist, outperforming CBDA, CBD, or THC in its potential impact. PPARs serve as ligand-binding transcription factors that selectively target cancer cells while sparing normal cells. The synergistic effects of THCA with other cytotoxic agents emphasize its potential in cancer therapy.
Equal concentrations of THC and CBD, when combined with THCA, CBDA, and cytotoxic terpenoids like limonene, hold significant promise in cancer treatment, as indicated by a study in the Planta Medicine Journal. Disposable cannabis pens can incorporate these cannabinoids and terpenes into a single cartridge.
Parkinson’s Disease
An observational study revealed that 22 out of 28 patients could tolerate smoked cannabis, presumably THC-predominant. The study illustrated acute benefits, including improvements in tremor, rigidity, and bradykinesia among participants.
In Parkinson’s disease, the loss of cells in the substantia nigra leads to widespread pathology over time. Tau proteins, which support the cytoskeleton and facilitate axonal transport in neurons, undergo changes that result in neurofibrillary tangles.
Nabiximols, a cannabis-based oral spray, significantly reduced tangles when administered to parkin-null mice expressing human tau. This treatment enhanced dopamine metabolism and glial function while reducing oxidative stress levels.
THC vape pens like cannabis can be an excellent choice for those seeking to improve tremors.
Alzheimer’s Disease
Alzheimer’s disease (AD) involves the formation of senile plaques from β-amyloid (Aβ) proteins, which occur when enzymes cleave a precursor protein (APP). It also involves the accumulation of neurofibrillary tangles from tau proteins with excessive phosphate groups. These tangles sometimes appear before the β-amyloid plaques. Once initiated, the progression of the disease is relentless.
CBD acts as a protective antioxidant for the brain, interacting safely with NMDA receptors. It performs several functions in combating Alzheimer’s disease: it halts the formation of Aβ plaques, reduces harmful ROS production, and protects fats in PC12 cells exposed to Aβ. CBD also prevents tau proteins from acquiring excessive phosphate groups in PC12 neurons affected by Aβ.
In a study, patients received THC-predominant (2.5–30 mg/dose), CBD-predominant, and THCA, primarily through tinctures and confections. Patients experienced reduced dependence on neuroleptic drugs, alleviated agitation, enhanced appetite, managed aggression, improved sleep quality, elevated mood, decreased demands for nursing care, mitigated self-harm tendencies, and controlled pain.
Cannabis components demonstrate the potential to address various symptoms associated with this complex disorder:
- Agitation may find relief with THC, CBD, and linalool.
- Psychotic symptoms may benefit from CBD.
- THC and linalool may ease insomnia and restlessness.
- THC is indicated for anorexia, while THC, CBD, and linalool may assist with aggression.
- THC, limonene, and CBD could potentially aid in managing depression.
- THC and CBD have pain-relieving properties.
- Alpha-pinene, alongside THC, is associated with memory enhancement.
- CBD and THC are linked to neuroprotection, while THC, CBD, and THCA may help reduce Aβ plaque formation.
Traumatic Brain Injury / Chronic Traumatic Encephalopathy
Cannabis, particularly chemovars combining THC and CBD, can mitigate symptoms linked with CTE, including headache, nausea, insomnia, dizziness, agitation, substance abuse, and psychotic symptoms.
A 2019 study indicated that varying concentrations of THC and CBD contribute to alleviating stress, agitation, depression, and anxiety—common emotional responses in chronic traumatic encephalopathy cases. Cannabinoids aid in reducing glutamate excitotoxicity, a process leading to nerve cell damage following a traumatic brain injury.
Want to Use cannabis for Your Current Condition?
Engaging in cannabis use is a popular approach to harness its benefits. If you’re aiming to avoid the potential health risks associated with traditional methods, cannabis vapes offer a practical alternative.
cannabis features a heating chamber or element that vaporizes the flower or concentrate. Online cannabis stores provide a wide array of options to help you find the ideal vape pen for your needs. You can choose based on the pen type, including disposable vape pens, and whether you prefer Sativa-dominant or Indica-dominant cartridges with high THC or specific concentrates.
Weed Vape Pens Treat Your Condition
Neurological treatments for the conditions discussed in this article require significant advancements. Nevertheless, emerging methods like using cannabis through cannabis in treatment protocols show promise. Research studies and anecdotal evidence suggest that cannabis, with its varying levels of THC, CBD, and other compounds, can interact with the ECS to help manage symptoms of these conditions.
Frequently Asked Questions
Can a dab pen provide the same experience as a vape pen?
A dab pen and a vape pen both vaporize cannabis concentrates but differ in intensity and usage. Dab pens cater to solid concentrates like wax and yield a more intense effect, while vape pens utilize liquid concentrates, providing a milder, more controlled experience.
Are THC pens cheap?
The average price for a cannabis pen is around $50. You can find options as low as $20 and others reaching $200 or more. Price variation depends on battery life and the range of features available.
Can my current medication interact with the active ingredient in my cannabis vape?
This will depend on your prescribed medication. If you take anti-depressants while managing Parkinson’s disease, cannabis could potentially lead to an initial increase in serotonin levels. This might heighten the body’s reliance on these substances, potentially worsening depression and anxiety over time. It’s advisable to consult your doctor before adding cannabis to your current medication regimen.
Are cannabis pens the best alternative when treating health issues with cannabis?
Weed pens provide a cleaner method of using cannabis without the harmful smoke associated with combustion. This makes them a preferred choice for individuals seeking a less damaging and more discreet option to address health issues like pain and anxiety.
However, whether cannabis pens are the optimal choice can vary for each user. As we continue to learn about their long-term effects, it’s crucial for anyone considering their use for health reasons to consult a doctor first. This helps ensure they are selecting the most suitable method for their health needs.
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