Emotionally Unstable Personality Disorder (EUPD), commonly referred to as Borderline Personality Disorder (BPD), significantly impacts social interactions, mood regulation, and may result in impulsive or self-destructive actions. Treatment costs can be high, with success rates varying from 35% to 50%. Research is currently focusing on alternative therapies to enhance traditional treatment methods.
A noteworthy option for EUPD management is cannabis, often called weed. Its affordability and beneficial components can aid EUPD patients. Those on a budget may seek out cheap cannabis online options for more economical solutions.
Table of Contents
Key Takeaways:
- Individuals with EUPD using THC or high CBD report positive outcomes in symptom management.
- High CBD doses (800 mg/day) and THC can elevate levels of anandamide in the body.
- Dysfunction within the endocannabinoid system, which manages emotions and stress, plays a role in Emotionally Unstable Personality Disorder.
Understanding EUPD or BPD
EUPD is a mental health issue that influences self-perception and interpersonal relationships, often resulting in challenges in everyday life. It is characterized by volatile relationships, impulsivity, and an inconsistent self-image.
Although its specific origins are unclear, factors like genetics, trauma, and neurotransmitter imbalances may contribute. Issues within the endocannabinoid system that governs emotions and stress could exacerbate EUPD symptoms.
EUPD Treatment
Clinical guidelines indicate that no medications are proven effective for EUPD; however, clinicians may prescribe antipsychotics and antidepressants.
Antipsychotic and sedative drugs can be beneficial for short-term crisis management or treating co-occurring disorders. Reports suggest that nearly 90% of EUPD patients take at least one psychotropic medication, including antipsychotics, antidepressants, mood stabilizers, and sedatives.
Polypharmacy is prevalent among these individuals, with many medications linked to side effects and often prescribed off-label for EUPD. While some can alleviate specific symptoms, they do not alter the overall prognosis of the disorder.
Cannabis-Based Medicine for EUPD (CBM)
Cannabis-based medicines are derived from the cannabis plant and contain cannabinoids, the active compounds like tetrahydrocannabinol (THC) and cannabidiol (CBD). These products address various medical conditions, including pain, anxiety, and inflammation.
Numerous studies are investigating the effects of cannabis on mental health. Research published in Frontiers in Psychiatry suggests that marijuana can alleviate depression and improve sleep quality and overall well-being, providing a strong rationale for further studies on cannabis’s impact on mental health disorders.
CBM for Unstable Personality Disorder
A 2022 study reviewed the use of cannabinoids for EUPD symptoms in seven patients, examining cellular and molecular mechanisms and current evidence supporting cannabis-based medicinal products (CBMP) as a treatment option for EUPD.
Materials and Methods
Participants were diagnosed with EUPD and had previously tried at least one medication and one psychotherapy form, with follow-up reviews at a Zerenia clinic documenting patient-reported outcomes.
CBM utilized included dried flower for inhalation (20-60g monthly) and oral extracts with THC (9-10mg/day) and CBD (40mg/day). Formulations included three chemotypes: high THC/low CBD, balanced THC and CBD, and high CBD/low THC.
Measurements were taken using the Clinical Global Impression Improvement (CGI-I) Scale and the Patient’s Global Impression of Change (PGIC) Scale, assessing improvements in symptoms.
Researchers personalized dosing through gradual titration, adjusting doses until patients achieved sufficient symptom control or reported side effects.
Results
After one month, six participants reported improvements, with five rating their progress as a six on the PGIC scale. One patient receiving chemotype 2 oral extract reported no benefits, indicating that inhaled THC or higher oral CBD doses may yield better results.
All participants tolerated the treatment well with no reported side effects, crucial for treatment adherence. Younger patients might feel more confident using medical cannabis despite social stigma.
Hypothesis
Researchers propose that exogenous cannabinoids can restore the endocannabinoid system’s tonic activation in the central nervous system (CNS). THC activates presynaptic CB1 receptors, and both cannabinoids attach to fatty-acid binding proteins (FABPs), potentially prolonging the effects of anandamide.
High oral CBD doses (800 mg/day) and patients using chemotype 1 flower show increased circulating anandamide levels. It’s unclear if this results from CBD affecting transport or degradation or other molecular interactions. In contrast, psychiatric medications typically require 2-3 weeks for initial effects and longer for remission.
Rapid symptom relief is essential during an “EUPD crisis,” when patients may resort to benzodiazepines and anxiety medications, which can lead to tolerance and dependency.
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Frequently Asked Questions
Does cheap marijuana have poor quality?
No, price isn’t the sole determinant of cannabis quality. Assess quality by examining the product’s characteristics and personal experience. Some dispensaries reduce prices during monthly or clearance sales. If a dispensary’s prices are significantly lower than industry standards, it may raise quality concerns.
Does marijuana cause adverse effects when managing BPD?
Participants in the study reported no adverse effects from marijuana. This is crucial for medication adherence, as a review of 36 studies found that side effects contributed to 28% of non-adherence to antipsychotics. Negative perceptions regarding antipsychotic medication were the second most common reason for intentional non-adherence, at 30.5%.
What is the quickest way to experience the effects of cannabinoids for an EUPD issue?
Smoking, vaping, and dabbing are the fastest ways to feel cannabinoid effects. In the study, participants vaped dried flower. While smoking and vaping produce similar effects, the distinction lies between inhaling smoke versus vapor. Dabbing, involving concentrates, also offers rapid effects.
How many times can I smoke or vape to manage my symptoms?
The effectiveness of cannabis strains and products varies for each individual. In the study, patients could modify their daily doses (between 0.5 and 2 grams per day) without exceeding the monthly limit. For extracts, patients recorded their daily dosages.
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